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Supramolecular Catalysis: An Efficient and Sustainable Multicomponent Approach to the Synthesis of Novel Hexahydro-4H-indazol-4-one Derivatives

Author(s):

Jyoti Tiwari, Swastika Singh, Deepali Jaiswal, Amit Kumar Sharma, Shailesh Singh, Jaya Singh and Jagdamba Singh*   Pages 1 - 10 ( 10 )

Abstract:


We have developed an efficient, novel one-pot multicomponent protocol for the synthesis of hexahydro-4H-indazol-4-one derivatives using b-cyclodextrin as a biomimetic catalyst in an aqueous medium. To the best of our knowledge, the targeted molecules have not been reported in the literature till now. The present method is very effective for our densely functionalized and diversified targeted molecules and includes several advantages like environment benign, cost-effectiveness, short reaction times, high yields and recyclability of the catalyst.

Keywords:

β-Cyclodextrin, One-pot, Green synthesis, Phase transfer catalyst, hexahydro-4H-indazol-4-one.

Affiliation:

Environmentally Benign Synthesis Lab, Department of Chemistry, University of Allahabad, Allahabad-211002, Department of Chemistry, S SKhannaPG College, Allahabad-211003, Environmentally Benign Synthesis Lab, Department of Chemistry, University of Allahabad, Allahabad-211002, Environmentally Benign Synthesis Lab, Department of Chemistry, University of Allahabad, Allahabad-211002, Environmentally Benign Synthesis Lab, Department of Chemistry, University of Allahabad, Allahabad-211002, Department of Chemistry, LRPG College, Sahibabad, Ghaziabad-201005, Environmentally Benign Synthesis Lab, Department of Chemistry, University of Allahabad, Allahabad-211002



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