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Supramolecular Catalysis: An Efficient and Sustainable Multicomponent Approach to the Synthesis of Novel Hexahydro-4H-indazol-4-one Derivatives

[ Vol. 9 , Issue. 2 ]

Author(s):

Jyoti Tiwari, Swastika Singh, Deepali Jaiswal, Amit Kumar Sharma, Shailesh Singh, Jaya Singh and Jagdamba Singh*   Pages 92 - 101 ( 10 )

Abstract:


We have developed an efficient, novel one-pot multicomponent protocol for the synthesis of hexahydro-4H-indazol-4-onederivatives using β-cyclodextrin as a biomimetic catalyst in an aqueous medium. To the best of our knowledge, the targeted molecules have not been reported in the literature till now. The present method is very effective for our densely functionalized and diversified targeted molecules and includes several advantages like environment benign, cost-effectiveness, short reaction times, high yields and recyclability of the catalyst.

Keywords:

β-Cyclodextrin, one-pot, green synthesis, phase transfer catalyst, hexahydro-4H-indazol-4-one, aqueous medium.

Affiliation:

Department of Chemistry, Environmentally Benign Synthesis Lab, University of Allahabad, Allahabad-211002, Department of Chemistry, S SKhannaPG College, Allahabad-211003, Department of Chemistry, Environmentally Benign Synthesis Lab, University of Allahabad, Allahabad-211002, Department of Chemistry, Environmentally Benign Synthesis Lab, University of Allahabad, Allahabad-211002, Department of Chemistry, Environmentally Benign Synthesis Lab, University of Allahabad, Allahabad-211002, Department of Chemistry, LRPG College, Sahibabad, Ghaziabad-201005, Department of Chemistry, Environmentally Benign Synthesis Lab, University of Allahabad, Allahabad-211002

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